UPSC Notes

Sickle Cell Disease (SCD) in India

PYQs

2

Articles

1

Momentum

9

Phase IFoundation

Background

Overview

UPSC examines public health challenges, genetic disorders, and their disproportionate impact on vulnerable populations like tribal communities, along with the socio-economic implications and government responses.

Sickle Cell Disease (SCD) is a genetic blood disorder characterized by abnormally shaped red blood cells, leading to chronic anaemia, pain crises, and organ damage. In India, it is a significant public health challenge, particularly prevalent among certain tribal and marginalized communities due to genetic factors.

Phase IIStatic core

Facts & tables

Key facts

Nature of Disease

Genetic blood disorder affecting red blood cells, leading to chronic anaemia and complications.

Affected Population

High prevalence in tribal-dominated areas across 17 states in India.

Symptoms & Complications

Chronic anaemia, severe pain episodes (crises), increased susceptibility to infections, organ damage.

Management Strategies

Includes Hydroxyurea, folic acid supplementation, counselling, and crisis management.

Reference table

Identified SCD Cases and Carriers (as on 16.07.2026)

CategoryTotal Individuals
Diseased247,961
Carriers2,035,181

Reference table

Static syllabus anchors

TypeReference
Conceptual areaMicrobiology & Epidemiology
Conceptual areaWelfare Schemes & Social Policies

Reference table

Institutions & roles

BodyRole
Ministry of Health & Family Welfare (MoH&FW)Provides technical and financial support for screening and treatment
Phase IIIExam lens

Prelims angle

Overview

Prelims angle: Multi-statement analysis

Prelims angle: Factual recall

Quick revision

  • Genetic blood disorder, prevalent in tribal areas.
  • Causes anaemia, pain crises, organ damage.
  • Managed with Hydroxyurea, folic acid, counselling.
  • Targeted by NSCAEM for elimination by 2047.
  • Screening for 0-40 years in 17 tribal states.

Topic timeline

Microbiology & EpidemiologyWelfare Schemes & Social Policies

Related topics

Practice writing on this topic

UPSC has asked 2 linked questions on Sickle Cell Disease (SCD) in India in Mains. Write an answer to one — and get it evaluated.